American film, stage, and television actress, producer, presenter, and health activist. Delany has been active in show business since the late 1970s. Following small roles early in her career, Delany garnered her first leading role in 1987 in the short-lived NBC sitcom Sweet Surrender and achieved wider fame in 1988–1991 as Colleen McMurphy on the ABC television show China Beach, for which she won two Primetime Emmy Awards (1989, 1992). She received further recognition for her performances in the films Light Sleeper (1992), Tombstone (1993), Exit to Eden (1994), The Margaret Sanger Story (1995), Fly Away Home (1996), True Women (1997), and Wide Awake (1998). Since the mid-1990s, Delany has served on the board of the Scleroderma Research Foundation.
In the 2000s, Delany returned to television with a string of short-lived television series beginning with Pasadena (2001), Presidio Med (2002–2003), and Kidnapped (2006–2007). From 2007 to 2010, Delany played Katherine Mayfair on the ABC series Desperate Housewives.
In the 2010s, from 2011 to 2013, Delany played the lead role of Megan Hunt on the ABC drama series Body of Proof. In 2014, she began her co-starring role as Crystal Harris in the Amazon drama series Hand of God, which has been ordered to full series by Amazon Studios in October 2014.
In 2015, she had a recurring guest role in the short-lived FX sitcom The Comedians as Julie, the wife of Billy Crystal, playing a fictionalized version of himself.
Delany is also a voice actress. She played Lois Lane in the DC animated universe as well as in The Batman animated series. In an interview, she said she loves to play “complicated characters”.

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